The effects of splenectomy in murine models of ischemic stroke: a systematic review and meta-analysis

Abstract Background The spleen, a substantial reservoir of non-differentiated monocytes, may play a crucial role in the pathophysiology of post-ischemic inflammation and influence outcomes after ischemic stroke. Aim of the study To analyze splenectomy as a preclinical intervention in murine models o...

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Bibliographic Details
Main Authors: Marko Sternak, Anton Glasnović, Paula Josić, Dominik Romić, Srećko Gajović
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:https://doi.org/10.1186/s12974-022-02593-w