Autologous skin-derived neural precursor cell therapy reverses canine Alzheimer dementia-like syndrome in a proof of concept veterinary trial

Abstract Background Older companion dogs naturally develop a dementia-like syndrome with biological, clinical and therapeutic similarities to Alzheimer disease (AD). Given there has been no new safe, clinically effective and widely accessible treatment for AD for almost 20 years, an all-new cell the...

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Main Authors: Michael Valenzuela, T. Duncan, A. Abey, A. Johnson, C. Boulamatsis, M. A. Dalton, E. Jacobson, L. Brunel, G. Child, D. Simpson, M. Buckland, A. Lowe, J. Siette, F. Westbrook, P. McGreevy
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-022-02933-w