A back-door insight into the modulation of Src kinase activity by the polyamine spermidine

Src is a protein tyrosine kinase commonly activated downstream of transmembrane receptors and plays key roles in cell growth, migration, and survival signaling pathways. In conventional dendritic cells (cDCs), Src is involved in the activation of the non-enzymatic functions of indoleamine 2,3-dioxyg...

Full description

Bibliographic Details
Main Authors: Sofia Rossini, Marco Gargaro, Giulia Scalisi, Elisa Bianconi, Sara Ambrosino, Eleonora Panfili, Claudia Volpi, Ciriana Orabona, Antonio Macchiarulo, Francesca Fallarino, Giada Mondanelli
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/85872