Phosphodiesterase and psychiatric disorders: a two-sample Mendelian randomization study

Phosphodiesterase and psychiatric disorders: a two-sample Mendelian randomization study

Abstract Background Phosphodiesterases (PDEs) have been associated with psychiatric disorders in observational studies; however, the causality of associations remains unestablished. Methods Specifically, cyclic nucleotide PDEs were collected from genome-wide association studies (GWASs), including PD...

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Bibliographic Details
Main Authors: Miaomiao Jiang, Weiheng Yan, Yuyanan Zhang, Zhe Lu, Tianlan Lu, Dai Zhang, Jun Li, Lifang Wang
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Journal of Translational Medicine
Subjects:
Phosphodiesterase
Psychiatric disorders
cAMP
cGMP
Mendelian randomization study
Online Access:https://doi.org/10.1186/s12967-023-04368-0

Internet

https://doi.org/10.1186/s12967-023-04368-0

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