Fragment-sequencing unveils local tissue microenvironments at single-cell resolution

Abstract Cells collectively determine biological functions by communicating with each other—both through direct physical contact and secreted factors. Consequently, the local microenvironment of a cell influences its behavior, gene expression, and cellular crosstalk. Disruption of this microenvironm...

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Bibliographic Details
Main Authors: Kristina Handler, Karsten Bach, Costanza Borrelli, Salvatore Piscuoglio, Xenia Ficht, Ilhan E. Acar, Andreas E. Moor
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43005-8