Mechanisms of Supralinear Calcium Integration in Dendrites of Hippocampal CA1 Fast-Spiking Cells

Mechanisms of Supralinear Calcium Integration in Dendrites of Hippocampal CA1 Fast-Spiking Cells

In fast-spiking (FS), parvalbumin-expressing interneurons of the CA1 hippocampus, activation of the GluA2-lacking Ca2+-permeable AMPA receptors (CP-AMPARs) in basal dendrites is coupled to Ca2+-induced Ca2+-release (CICR), and can result in a supralinear summation of postsynaptic Ca2+-transients (po...

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Bibliographic Details
Main Authors: Olivier Camiré, Ivan Lazarevich, Tommy Gilbert, Lisa Topolnik
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
Ca2+-permeable AMPA receptor
glutamate
excitatory current
synaptic plasticity
ryanodine receptor
Online Access:https://www.frontiersin.org/article/10.3389/fnsyn.2018.00047/full

Internet

https://www.frontiersin.org/article/10.3389/fnsyn.2018.00047/full

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