Mitochondrial DNA methylation in metabolic associated fatty liver disease

Mitochondrial DNA methylation in metabolic associated fatty liver disease

IntroductionHepatic lipid accumulation and mitochondrial dysfunction are hallmarks of metabolic associated fatty liver disease (MAFLD), yet molecular parameters underlying MAFLD progression are not well understood. Differential methylation within the mitochondrial DNA (mtDNA) has been suggested to b...

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Bibliographic Details
Main Authors: Archibold Mposhi, Fabian Cortés-Mancera, Janette Heegsma, Vincent E. de Meijer, Bart van de Sluis, Svenja Sydor, Lars P. Bechmann, Claudia Theys, Peter de Rijk, Tim De Pooter, Wim Vanden Berghe, İkbal Agah İnce, Klaas Nico Faber, Marianne G. Rots
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Nutrition
Subjects:
liver steatosis
NAFLD
NASH
ND6
mtDNA methylation
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2023.964337/full

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https://www.frontiersin.org/articles/10.3389/fnut.2023.964337/full

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