The role of tumor necrosis factor-α and TNF-α receptors in cerebral arteries following cerebral ischemia in rat
<p>Abstract</p> <p>Background</p> <p>Tumour necrosis factor-α (TNF-α) is a pleiotropic pro-inflammatory cytokine, which is rapidly upregulated in the brain after injury. TNF-α acts by binding to its receptors, TNF-R1 (p55) and TNF-R2 (p75), on the cell surface. The aim...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-08-01
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Series: | Journal of Neuroinflammation |
Online Access: | http://www.jneuroinflammation.com/content/8/1/107 |