The role of tumor necrosis factor-α and TNF-α receptors in cerebral arteries following cerebral ischemia in rat

The role of tumor necrosis factor-α and TNF-α receptors in cerebral arteries following cerebral ischemia in rat

<p>Abstract</p> <p>Background</p> <p>Tumour necrosis factor-α (TNF-α) is a pleiotropic pro-inflammatory cytokine, which is rapidly upregulated in the brain after injury. TNF-α acts by binding to its receptors, TNF-R1 (p55) and TNF-R2 (p75), on the cell surface. The aim...

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Bibliographic Details
Main Authors:	Chen Qing-Wen, Kruse Lars S, Maddahi Aida, Edvinsson Lars
Format:	Article
Language:	English
Published:	BMC 2011-08-01
Series:	Journal of Neuroinflammation
Online Access:	http://www.jneuroinflammation.com/content/8/1/107

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