Apoptosis mediated leishmanicidal activity of Azadirachta indica bioactive fractions is accompanied by Th1 immunostimulatory potential and therapeutic cure in vivo

Apoptosis mediated leishmanicidal activity of Azadirachta indica bioactive fractions is accompanied by Th1 immunostimulatory potential and therapeutic cure in vivo

Abstract Background Exploration of immunomodulatory antileishmanials of plant origin is now being strongly recommended to overcome the immune suppression evident during visceral leishmaniasis (VL) and high cost and toxicity associated with conventional chemotherapeutics. In accordance, we assessed t...

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Bibliographic Details
Main Authors: Garima Chouhan, Mohammad Islamuddin, Muzamil Y Want, Malik Z Abdin, Hani A Ozbak, Hassan A Hemeg, Dinkar Sahal, Farhat Afrin
Format: Article
Language:English
Published: BMC 2015-03-01
Series:Parasites & Vectors
Subjects:
Visceral Leishmaniasis
Leishmania donovani
Apoptosis
Immunomodulatory
Antileishmanial
Immunopotentiating
Online Access:https://doi.org/10.1186/s13071-015-0788-3

Internet

https://doi.org/10.1186/s13071-015-0788-3

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