The Multifunctional Role of Poloxamer P338 as a Biofilm Disrupter and Antibiotic Enhancer: A Small Step forward against the Big Trouble of Catheter-Associated <i>Escherichia coli</i> Urinary Tract Infections

The Multifunctional Role of Poloxamer P338 as a Biofilm Disrupter and Antibiotic Enhancer: A Small Step forward against the Big Trouble of Catheter-Associated <i>Escherichia coli</i> Urinary Tract Infections

Poloxamer 338 (P338), a nonionic surfactant amphiphilic copolymer, is herein proposed as an anti-biofilm compound for the management of catheter-associated urinary tract infections (CAUTIs). P338’s ability to disrupt <i>Escherichia coli</i> biofilms on silicone urinary catheters and to s...

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Bibliographic Details
Main Authors: Lucia Henrici De Angelis, Mariarita Stirpe, Dario Tomolillo, Gianfranco Donelli, Iolanda Francolini, Claudia Vuotto
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Microorganisms
Subjects:
Poloxamer P338
biofilm disruption
catheter-associated urinary tract infections
<i>E. coli</i>
antibiotic enhancer
Online Access:https://www.mdpi.com/2076-2607/10/9/1757

Internet

https://www.mdpi.com/2076-2607/10/9/1757

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