Patchouli alcohol induces G0/G1 cell cycle arrest and apoptosis in vincristine‐resistant non‐small cell lung cancer through ROS‐mediated DNA damage

Patchouli alcohol induces G0/G1 cell cycle arrest and apoptosis in vincristine‐resistant non‐small cell lung cancer through ROS‐mediated DNA damage

Abstract Background Lung cancer, especially non‐small cell lung cancer (NSCLC), is one of the leading causes of cancer‐related deaths worldwide. Vincristine (VCR) is a chemotherapeutic agent for lung cancers; however, its effectiveness is limited by side effects and the development of drug resistanc...

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Bibliographic Details
Main Authors: Chi‐Yen Liang, Kai‐Fu Chang, Ya‐Chih Huang, Xiao‐Fan Huang, Gwo‐Tarng Sheu, Chia‐Feng Kuo, Chih‐Yen Hsiao, Nu‐Man Tsai
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Thoracic Cancer
Subjects:
apoptosis
non‐small cell lung cancer
patchouli alcohol
ROS
vincristine resistance
Online Access:https://doi.org/10.1111/1759-7714.14982

Internet

https://doi.org/10.1111/1759-7714.14982

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