Novel role of miR-133a-3p in repressing gastric cancer growth and metastasis via blocking autophagy-mediated glutaminolysis

Novel role of miR-133a-3p in repressing gastric cancer growth and metastasis via blocking autophagy-mediated glutaminolysis

Abstract Background Autophagy plays a crucial role in sustaining the homeostasis in various malignant diseases. It has also been reported to promote tumor development in multiple cancers. Glutaminolysis instead of Warburg Effect produce adequate ATP and provide nitrogen and carbon to replenish the T...

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Bibliographic Details
Main Authors: Xing Zhang, Zheng Li, Zhe Xuan, Penghui Xu, Weizhi Wang, Zheng Chen, Sen Wang, Guangli Sun, Jianghao Xu, Zekuan Xu
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Gastric cancer
Autophagy
Glutaminolysis
miRNA
Organoid
GABARAPLI
Online Access:http://link.springer.com/article/10.1186/s13046-018-0993-y

Internet

http://link.springer.com/article/10.1186/s13046-018-0993-y

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