Safety pharmacology of self-assembled-micelle inhibitory RNA-targeting amphiregulin (SAMiRNA-AREG), a novel siRNA nanoparticle platform

Safety pharmacology of self-assembled-micelle inhibitory RNA-targeting amphiregulin (SAMiRNA-AREG), a novel siRNA nanoparticle platform

The present safety pharmacology core battery studies (neurobehavior, respiratory, cardiovascular system, and human ether a-go-go (hERG) channel current) investigated the potential harmful effects of self-assembled-micelle inhibitory RNA-targeting amphiregulin (SAMiRNA-AREG). The SAMiRNA-AREG was adm...

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Bibliografiske detaljer
Main Authors: Tae Rim Kim, Hyeon-Young Kim, In-Hyeon Kim, Ki Cheon Kim, Youngho Ko, Jun Hong Park, Sungil Yun, In-Chul Lee, Sung-Hwan Kim, Han-Oh Park
Format: Article
Sprog:English
Udgivet: Elsevier 2021-01-01
Serier:Toxicology Reports
Fag:
Self-assembled-micelle inhibitory RNA nanoparticle
Amphiregulin
Safety pharmacology
Core battery
Online adgang:http://www.sciencedirect.com/science/article/pii/S2214750021000639

Internet

http://www.sciencedirect.com/science/article/pii/S2214750021000639

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