Structural and functional implications of SLC13A3 and SLC9A6 mutations: an in silico approach to understanding intellectual disability

Structural and functional implications of SLC13A3 and SLC9A6 mutations: an in silico approach to understanding intellectual disability

Abstract Background Intellectual disability (ID) is a condition that varies widely in both its clinical presentation and its genetic underpinnings. It significantly impacts patients’ learning capacities and lowers their IQ below 70. The solute carrier (SLC) family is the most abundant class of trans...

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Bibliographic Details
Main Authors: Syeda Iqra Hussain, Nazif Muhammad, Salah Ud Din Shah, Fardous Fardous, Sher Alam Khan, Niamatullah Khan, Adil U Rehman, Mehwish Siddique, Shoukat Ali Wasan, Rooh Niaz, Hafiz Ullah, Niamat Khan, Noor Muhammad, Muhammad Usman Mirza, Naveed Wasif, Saadullah Khan
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Neurology
Subjects:
Intellectual disability
Acute reversible leukoencephalopathy
Christianson Syndrome
Exome sequencing
SLC13A3
SLC9A6
Online Access:https://doi.org/10.1186/s12883-023-03397-y

Internet

https://doi.org/10.1186/s12883-023-03397-y

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