The effect of methanol fixation on single-cell RNA sequencing data

Abstract Background Single-cell RNA sequencing (scRNA-seq) has led to remarkable progress in our understanding of tissue heterogeneity in health and disease. Recently, the need for scRNA-seq sample fixation has emerged in many scenarios, such as when samples need long-term transportation, or when ex...

Full description

Bibliographic Details
Main Authors: Xinlei Wang, Lei Yu, Angela Ruohao Wu
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-021-07744-6