Biglycan as a potential regulator of tumorgenicity and immunogenicity in K-RAS-transformed cells

Biglycan as a potential regulator of tumorgenicity and immunogenicity in K-RAS-transformed cells

The extracellular matrix component biglycan (BGN) plays an essential role in various physiological and pathophysiological processes. A deficient BGN expression associated with reduced immunogenicity was found in HER-2/neu-overexpressing cells. To determine whether BGN is suppressed by oncogene-drive...

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Bibliographic Details
Main Authors: Karthikeyan Subbarayan, Chiara Massa, Sandra Leisz, André Steven, Daniel Bethmann, Katharina Biehl, Claudia Wickenhauser, Barbara Seliger
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:OncoImmunology
Subjects:
Immune escape
oncogene
K-RAS
colorectal carcinoma
proteoglycan
MHC class I
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2022.2069214

Internet

https://www.tandfonline.com/doi/10.1080/2162402X.2022.2069214

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