Effectiveness and safety of multidrug therapy containing clofazimine for paucibacillary leprosy and clarithromycin for rifampicin-resistant leprosy: a systematic review and meta-analysis

Effectiveness and safety of multidrug therapy containing clofazimine for paucibacillary leprosy and clarithromycin for rifampicin-resistant leprosy: a systematic review and meta-analysis

IntroductionThe present study aimed to evaluate leprosy cure and relapse rates as primary outcomes related to two additional strategies for leprosy treatment: clofazimine for paucibacillary (PB) leprosy patients and clarithromycin for patients with rifampicin-resistant leprosy.MethodsWe conducted tw...

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Bibliographic Details
Main Authors: Thais Montezuma, Sebastian Vernal, Elaine Nascimento Andrade, Jurema Guerrieri Brandão, Gustavo Laine Araújo de Oliveira, Ciro Martins Gomes
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Medicine
Subjects:
leprosy
meta-analysis
drug resistance
microbial
GRADE approach
systematic review
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1139304/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2023.1139304/full

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