Interaction of genetic variation at ADH1B and MLXIPL with alcohol consumption for elevated serum urate level and gout among people of European ethnicity

Interaction of genetic variation at ADH1B and MLXIPL with alcohol consumption for elevated serum urate level and gout among people of European ethnicity

Abstract Background Alcohol consumption is a risk factor for hyperuricaemia and gout. Multiple single-nucleotide polymorphisms (SNPs) have been identified as associated with both alcohol consumption and serum urate or gout in separate genome-wide association studies (GWAS). This study aimed to ident...

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Bibliographic Details
Main Authors: Min H Chuah, Megan P Leask, Ruth K Topless, Gregory D Gamble, Nicholas A Sumpter, Lisa K Stamp, Tony R Merriman, Nicola Dalbeth
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Arthritis Research & Therapy
Subjects:
Urate
Hyperuricaemia
Gout
Alcohol
Single-nucleotide polymorphism
ADH1B
Online Access:https://doi.org/10.1186/s13075-024-03279-9

Internet

https://doi.org/10.1186/s13075-024-03279-9

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