Oxidative Stress and Analysis of Selected SNPs of <i>ACHE</i> (rs 2571598), <i>BCHE</i> (rs 3495), <i>CAT</i> (rs 7943316), <i>SIRT1</i> (rs 10823108), <i>GSTP1</i> (rs 1695), and Gene <i>GSTM1</i>, <i>GSTT1</i> in Chronic Organophosphates Exposed Groups from Cameroon and Pakistan

Oxidative Stress and Analysis of Selected SNPs of <i>ACHE</i> (rs 2571598), <i>BCHE</i> (rs 3495), <i>CAT</i> (rs 7943316), <i>SIRT1</i> (rs 10823108), <i>GSTP1</i> (rs 1695), and Gene <i>GSTM1</i>, <i>GSTT1</i> in Chronic Organophosphates Exposed Groups from Cameroon and Pakistan

The detrimental effects of organophosphates (OPs) on human health are thought to be of systemic, i.e., irreversible inhibition of acetylcholinesterase (AChE) at nerve synapses. However, several studies have shown that AChE inhibition alone cannot explain all the toxicological manifestations in prolo...

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Bibliographic Details
Main Authors: Leonel Javeres Mbah Ntepe, Rabia Habib, Ngondi Judith Laure, Saqlain Raza, Eugenie Nepovimova, Kamil Kuca, Sajida Batool, Syed Muhammad Nurulain
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
organophosphates
antioxidants
cholinergic enzymes
SNPs
toxicogenetics
Online Access:https://www.mdpi.com/1422-0067/21/17/6432

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https://www.mdpi.com/1422-0067/21/17/6432

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