Machine Learning Quantification of Amyloid Deposits in Histological Images of Ligamentum Flavum

Machine Learning Quantification of Amyloid Deposits in Histological Images of Ligamentum Flavum

Wild-type transthyretin amyloidosis (ATTRwt) is an underdiagnosed and potentially fatal disease. Interestingly, ATTRwt deposits have been found to deposit in the ligamentum flavum (LF) of patients with lumbar spinal stenosis before the development of systemic and cardiac amyloidosis. In order to stu...

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Bibliographic Details
Main Authors: Andy Y. Wang, Vaishnavi Sharma, Harleen Saini, Joseph N. Tingen, Alexandra Flores, Diang Liu, Mina G. Safain, James Kryzanski, Ellen D. McPhail, Knarik Arkun, Ron I. Riesenburger
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Journal of Pathology Informatics
Subjects:
Wild-type transthyretin amyloid
Ligamentum flavum
Trainable Weka Segmentation
Machine learning
Color thresholding
Online Access:http://www.sciencedirect.com/science/article/pii/S215335392200013X

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http://www.sciencedirect.com/science/article/pii/S215335392200013X

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