Mutations designed to modify the NS gene mRNA secondary structure affect influenza A pathogenicity in vivo

The influenza A virus genome consists of eight segments of negative-sense RNA that encode up to 18 proteins. During the process of viral replication, positive-sense (+)RNA (cRNA) or messenger RNA (mRNA) is synthesized. Today, there is only a partial understanding of the function of several secondary...

Full description

Bibliographic Details
Main Authors: Irina L. Baranovskaya, Mariia V. Sergeeva, Aleksandr S. Taraskin, Alexey A. Lozhkov, Andrey V. Vasin
Format: Article
Language:English
Published: Doctrine 2021-02-01
Series:Microbiology Independent Research Journal
Online Access:https://www.scienceopen.com/hosted-document?doi=10.18527/2500-2236-2021-8-1-1-9