Effects of AM80 compared to AC261066 in a high fat diet mouse model of liver disease.

The roles of retinoids in nonalcoholic fatty liver disease (NAFLD) remain unclear and a better understanding may lead to therapies that prevent or limit NAFLD progression. We examined the actions of retinoic acid receptor (RAR) agonists- AM80 for RARα and AC261066 for RARβ2- in a murine model of NAF...

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Bibliographic Details
Main Authors: Marta Melis, Xiao-Han Tang, Steven E Trasino, Viral M Patel, Daniel J Stummer, Jose Jessurun, Lorraine J Gudas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0211071