Structural models of genome-wide covariance identify multiple common dimensions in autism

Structural models of genome-wide covariance identify multiple common dimensions in autism

Abstract Common genetic variation has been associated with multiple phenotypic features in Autism Spectrum Disorder (ASD). However, our knowledge of shared genetic factor structures contributing to this highly heterogeneous phenotypic spectrum is limited. Here, we developed and implemented a structu...

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Bibliographic Details
Main Authors: Lucía de Hoyos, Maria T. Barendse, Fenja Schlag, Marjolein M. J. van Donkelaar, Ellen Verhoef, Chin Yang Shapland, Alexander Klassmann, Jan Buitelaar, Brad Verhulst, Simon E. Fisher, Dheeraj Rai, Beate St Pourcain
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46128-8

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https://doi.org/10.1038/s41467-024-46128-8

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