Comparison of hepatic arterial infusion chemotherapy with mFOLFOX vs. first-line systemic chemotherapy in patients with unresectable intrahepatic cholangiocarcinoma

Comparison of hepatic arterial infusion chemotherapy with mFOLFOX vs. first-line systemic chemotherapy in patients with unresectable intrahepatic cholangiocarcinoma

Background: Systemic chemotherapy (SC) remains the only first-line treatment for unresectable intrahepatic cholangiocarcinoma (iCCA). Hepatic arterial infusion chemotherapy (HAIC) has been recently proven to be effective in managing hepatocellular carcinoma (HCC). Hence, our study aims to investigat...

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Bibliographic Details
Main Authors: Zhenyun Yang, Yizhen Fu, Weijie Wu, Zili Hu, Yangxun Pan, Juncheng Wang, Jinbin Chen, Dandan Hu, Zhongguo Zhou, Minshan Chen, Yaojun Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Pharmacology
Subjects:
intrahepatic cholangiocarcinoma
hepatic arterial infusion chemotherapy
systemic chemotherapy
overall survival
progression-free survival
adverse events
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1234342/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1234342/full

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