G-quadruplexes Mark Sites of Methylation Instability Associated with Ageing and Cancer

Regulation of the epigenome is critical for healthy cell function but can become disrupted with age, leading to aberrant epigenetic profiles including altered DNA methylation. Recent studies have indicated that DNA methylation homeostasis can be compromised by the formation of DNA secondary structur...

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Bibliographic Details
Main Authors: Jonas Rauchhaus, Jenna Robinson, Ludovica Monti, Marco Di Antonio
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/13/9/1665