Tau accumulation in degradative organelles is associated to lysosomal stress
Abstract Neurodegenerative disorders are characterized by the brain deposition of insoluble amyloidogenic proteins, such as α-synuclein or Tau, and the concomitant deterioration of cell functions such as the autophagy-lysosomal pathway (ALP). The ALP is involved in the degradation of intracellular m...
| প্রধান লেখক: | , , , , , , , |
|---|---|
| বিন্যাস: | প্রবন্ধ |
| ভাষা: | English |
| প্রকাশিত: |
Nature Portfolio
2023-10-01
|
| মালা: | Scientific Reports |
| অনলাইন ব্যবহার করুন: | https://doi.org/10.1038/s41598-023-44979-7 |