Dopamine receptor D3 signalling in astrocytes promotes neuroinflammation

Dopamine receptor D3 signalling in astrocytes promotes neuroinflammation

Abstract Background Neuroinflammation constitutes a pathogenic process leading to neurodegeneration in several disorders, including Alzheimer’s disease, Parkinson’s disease (PD) and sepsis. Despite microglial cells being the central players in neuroinflammation, astrocytes play a key regulatory role...

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Bibliographic Details
Main Authors: Andro Montoya, Daniela Elgueta, Javier Campos, Ornella Chovar, Paulina Falcón, Soledad Matus, Iván Alfaro, María Rosa Bono, Rodrigo Pacheco
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Journal of Neuroinflammation
Subjects:
Neuroinflammation
Astrocytes
Microglia
Dopamine receptors
Online Access:https://doi.org/10.1186/s12974-019-1652-8

Internet

https://doi.org/10.1186/s12974-019-1652-8

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