sBCMA Plasma Level Dynamics and Anti-BCMA CAR-T-Cell Treatment in Relapsed Multiple Myeloma

BACKGROUND: Novel chimeric antigen receptor T-cells (CAR-T) target the B-cell maturation antigen (BCMA) expressed on multiple myeloma cells. Assays monitoring CAR-T cell expansion and treatment response are being implemented in clinical routine. METHODS: Plasma levels of soluble BCMA (sBCMA) and ant...

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Bibliographic Details
Main Authors: Katja Seipel, Naomi Porret, Gertrud Wiedemann, Barbara Jeker, Vera Ulrike Bacher, Thomas Pabst
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Current Issues in Molecular Biology
Subjects:
Online Access:https://www.mdpi.com/1467-3045/44/4/98