Targeting the Early Endosome-to-Golgi Transport of Shiga Toxins as a Therapeutic Strategy
Shiga toxin (STx) produced by <i>Shigella</i> and closely related Shiga toxin 1 and 2 (STx1 and STx2) synthesized by Shiga toxin-producing <i>Escherichia coli</i> (STEC) are bacterial AB<sub>5</sub> toxins. All three toxins target kidney cells and may cause life-t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-05-01
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| Series: | Toxins |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6651/12/5/342 |