Development of a non-infectious control for viral hemorrhagic fever PCR assays.

Assay validation is an essential component of disease surveillance testing, but can be problematic in settings where access to positive control material is limited and a safety risk for handlers. Here we describe a single non-infectious synthetic control that can help develop and validate the PCR ba...

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Bibliographic Details
Main Authors: Matthew A Knox, Collette Bromhead, David Ts Hayman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0011390&type=printable