A Novel Homozygous Mutation in the COL4A4 Gene (Gly1436del) Causing Alport Syndrome Exposed by Pregnancy: A Case Report and Review of the Literature

Background. Alport syndrome results from a hereditary defect of collagen IV synthesis. This causes progressive glomerular disease, ocular abnormalities, and inner ear impairment. Case Presentation. Herein, we present a case of Alport syndrome in a 28-year-old woman caused by a novel mutation (Gly143...

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Bibliographic Details
Main Authors: Ulrich Jehn, Cornelie Müller-Hofstede, Barbara Heitplatz, Veerle Van Marck, Stefan Reuter, Hermann Pavenstädt, Britta George
Format: Article
Language:English
Published: Hindawi Limited 2022-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2022/5243137