Exosomes from cervical cancer cells facilitate pro-angiogenic endothelial reconditioning through transfer of Hedgehog–GLI signaling components

Exosomes from cervical cancer cells facilitate pro-angiogenic endothelial reconditioning through transfer of Hedgehog–GLI signaling components

Abstract Background Angiogenic switch is a hallmark feature of transition from low-grade to high-grade cervical intraepithelial neoplasia (CIN) in cervical cancer progression. Therefore, early events leading to locally-advanced cervical metastatic lesions demand a greater understanding of the underl...

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Bibliographic Details
Main Authors: Anjali Bhat, Joni Yadav, Kulbhushan Thakur, Nikita Aggarwal, Tanya Tripathi, Arun Chhokar, Tejveer Singh, Mohit Jadli, Alok Chandra Bharti
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Cancer Cell International
Subjects:
Cervical cancer
Exosome
Angiogenesis
Hh-GLI signaling
Tumor microenvironment
VEGF
Online Access:https://doi.org/10.1186/s12935-021-02026-3

Internet

https://doi.org/10.1186/s12935-021-02026-3

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