Finding a Toll on the Route: The Fate of Osteoclast Progenitors After Toll-Like Receptor Activation

Finding a Toll on the Route: The Fate of Osteoclast Progenitors After Toll-Like Receptor Activation

M-CSF and RANKL are two crucial cytokines stimulating differentiation of mature, bone resorbing, multinucleated osteoclasts from mononucleated progenitor cells in the monocyte/macrophage lineage. In addition to the receptors for M-CSF and RANKL, osteoclast progenitor cells express receptors for seve...

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Bibliographic Details
Main Authors: Pedro P. C. Souza, Ulf H. Lerner
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
toll-like receptors
osteoclast
lipopolysaccharide
RANKL
bone resorption
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01663/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01663/full

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