A review of the mechanisms of abnormal ceramide metabolism in type 2 diabetes mellitus, Alzheimer’s disease, and their co-morbidities

A review of the mechanisms of abnormal ceramide metabolism in type 2 diabetes mellitus, Alzheimer’s disease, and their co-morbidities

The global prevalence of type 2 diabetes mellitus (T2DM) and Alzheimer’s disease (AD) is rapidly increasing, revealing a strong association between these two diseases. Currently, there are no curative medication available for the comorbidity of T2DM and AD. Ceramides are structural components of cel...

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Bibliographic Details
Main Authors: Yun Pan, Jieying Li, Panjie Lin, Lihua Wan, Yiqian Qu, Lingyong Cao, Lei Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Pharmacology
Subjects:
ceramide
Alzheimer's disease
type 2 diabetes mellitus
insulin signaling
comorbidity
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1348410/full

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https://www.frontiersin.org/articles/10.3389/fphar.2024.1348410/full

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