Locus specific endogenous retroviral expression associated with Alzheimer’s disease

Locus specific endogenous retroviral expression associated with Alzheimer’s disease

IntroductionHuman endogenous retroviruses (HERVs) are transcriptionally-active remnants of ancient retroviral infections that may play a role in Alzheimer’s disease.MethodsWe combined two, publicly available RNA-Seq datasets with a third, novel dataset for a total cohort of 103 patients with Alzheim...

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Bibliographic Details
Main Authors: Tyson Dawson, Uzma Rentia, Jessie Sanford, Carlos Cruchaga, John S. K. Kauwe, Keith A. Crandall
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
HERV
endogenous retrovirus
RNA-Seq
gene expression
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1186470/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2023.1186470/full

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