Whole-exome sequencing in UK Biobank reveals rare genetic architecture for depression

Whole-exome sequencing in UK Biobank reveals rare genetic architecture for depression

Abstract Nearly two hundred common-variant depression risk loci have been identified by genome-wide association studies (GWAS). However, the impact of rare coding variants on depression remains poorly understood. Here, we present whole-exome sequencing analyses of depression with seven different def...

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Bibliographic Details
Main Authors: Ruoyu Tian, Tian Ge, Hyeokmoon Kweon, Daniel B. Rocha, Max Lam, Jimmy Z. Liu, Kritika Singh, Biogen Biobank Team, Daniel F. Levey, Joel Gelernter, Murray B. Stein, Ellen A. Tsai, Hailiang Huang, Christopher F. Chabris, Todd Lencz, Heiko Runz, Chia-Yen Chen
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45774-2

Internet

https://doi.org/10.1038/s41467-024-45774-2

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