Biochemical profiling of histone binding selectivity of the yeast bromodomain family.

It has been shown that molecular interactions between site-specific chemical modifications such as acetylation and methylation on DNA-packing histones and conserved structural modules present in transcriptional proteins are closely associated with chromatin structural changes and gene activation. Un...

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Bibliographic Details
Main Authors: Qiang Zhang, Suvobrata Chakravarty, Dario Ghersi, Lei Zeng, Alexander N Plotnikov, Roberto Sanchez, Ming-Ming Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2811197?pdf=render