Diverse effects of coronavirus-defective viral genomes on the synthesis of IFNβ and ISG15 mRNAs and coronavirus replication
Abstract Background The mechanism by which coronavirus-defective viral genomes (DVGs) affect coronavirus and host cells during infection remains unclear. A variety of DVGs with different RNA structures can be synthesized from coronavirus-infected cells, and these DVGs can also encode proteins. Conse...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
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Series: | Virology Journal |
Online Access: | https://doi.org/10.1186/s12985-025-02654-5 |