Distinct effects of Fgf7 and Fgf10 on the terminal differentiation of murine bladder urothelium revealed using an organoid culture system

Distinct effects of Fgf7 and Fgf10 on the terminal differentiation of murine bladder urothelium revealed using an organoid culture system

Abstract Background Dysregulation of the terminal differentiation of bladder urothelium is associated with the pathogenesis of urinary tract disorders. Fibroblast growth factor (Fgf)7 and Fgf10 stimulate urothelial proliferation; however, their roles in cellular differentiation remain unclear. In th...

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Bibliographic Details
Main Authors: Kazuto Suda, Yuka Matsumoto, Takanori Ochi, Hiroyuki Koga, Nobutaka Hattori, Atsuyuki Yamataka, Tetsuya Nakamura
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Urology
Subjects:
Bladder
Urothelium
Differentiation
Organoid
Fibroblast growth factor 7
Fibroblast growth factor 10
Online Access:https://doi.org/10.1186/s12894-023-01338-y

Internet

https://doi.org/10.1186/s12894-023-01338-y

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