Maternal behavior promotes resilience to adolescent stress in mice through a microglia-neuron axis

Abstract Early life experience modulates resilience to stress in later life. Previous research implicated maternal care as a key mediator of behavioral responses to the adversity in adolescence, but details of molecular mechanisms remain elusive. Here, we show social stress activates transcription f...

Full description

Bibliographic Details
Main Authors: Hongyu Chen, Ruifeng Xu, Jianhao Wang, Feng Gao, Yida Lv, Xiang Li, Fang Li, Junqin Zhao, Xi Zhang, Jiabei Wang, Ruicheng Du, Yuke Shi, Hang Yu, Shuai Ding, Wenxin Li, Jing Xiong, Jie Zheng, Liang Zhao, Xin-Ya Gao, Zhi-Hao Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57810-w