The Need for the Closer Monitoring of Novel Drugs in MS: A Siponimod Retrospective Cohort Study (Realhes Study)

The Need for the Closer Monitoring of Novel Drugs in MS: A Siponimod Retrospective Cohort Study (Realhes Study)

Background: Severe cases of lymphopenia have been reported during siponimod clinical trials, which may negatively impact its benefit/risk profile. Objective: We aimed to evaluate the incidence of lymphopenia following the initiation of siponimod treatment in clinical practice. The secondary objectiv...

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Bibliographic Details
Main Authors: Arantxa Sancho-López, Belén Ruiz-Antorán, Teresa Iglesias Hernangómez, Almudena Ramírez-García, Irene Gómez-Estévez, Judith Sanabria-Cabrera, Roser Llop Rius, Consuelo Pedrós, Diana Campodonico, Silvia Jiménez-Jorge, Amelia García Luque, Lucienne Costa Frossad França, Eva Montané, Ana Aldea-Perona, Nieves Téllez Lara, Montserrat Bosch Ferrer, Consuelo Rodriguez Jiménez, Elvira Bonilla-Toyos, Julia Sabín Muñoz, Cristina Avendaño-Solá, María Rosario Blasco Quilez, on behalf of the REALHES-Study Group
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Journal of Clinical Medicine
Subjects:
multiple sclerosis
siponimod
pharmacovigilance
lymphopenia
real-world evidence
Online Access:https://www.mdpi.com/2077-0383/12/20/6471

Internet

https://www.mdpi.com/2077-0383/12/20/6471

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