Role of TGF-beta1 and MAP kinases in the antiproliferative effect of aspirin in human vascular smooth muscle cells.

We aimed to test the antiproliferative effect of acetylsalicylic acid (ASA) on vascular smooth muscle cells (VSMC) from bypass surgery patients and the role of transforming growth factor beta 1 (TGF-beta1).VSMC were isolated from remaining internal mammary artery from patients who underwent bypass s...

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Bibliographic Details
Main Authors: Santiago Redondo, Emilio Ruiz, Antonio Gordillo-Moscoso, Jorge Navarro-Dorado, Marta Ramajo, Manuel Carnero, Fernando Reguillo, Enrique Rodriguez, Teresa Tejerina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2842433?pdf=render