NMDA Receptor-Antagonistic Properties of Hyperforin, a Constituent of St. John’s Wort

Extracts of the medicinal plant St. John’s wort (Hypericum perforatum) are widely used for the treatment of affective disorders. Hyperforin, a constituent of St. John’s wort, is known to modulate the release and re-uptake of various neurotransmitters, an action that likely underlies its antidepressi...

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Bibliographic Details
Main Authors: Vikas Kumar, Alexander Mdzinarishvili, Cornelia Kiewert, Thomas Abbruscato, Ulrich Bickel, Cornelis J. van der Schyf, Jochen Klein
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319344159