Metabolic actions of FGF21: molecular mechanisms and therapeutic implications

Metabolic actions of FGF21: molecular mechanisms and therapeutic implications

Fibroblast growth factor 21 (FGF21) is an atypical member of the FGF family that functions as an endocrine factor. In obese animals, elevation of plasma FGF21 levels by either pharmacological or genetic approaches reduces body weight, decreases hyperglycemia and hyperlipidemia, alleviates fatty live...

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Bibliographic Details
Main Authors: Xuan Ge, Yu Wang, Karen SL Lam, Aimin Xu
Format: Article
Language:English
Published: Elsevier 2012-08-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Metabolic hormones
Obesity
Diabetes
FGF21
Energy homeostasis
Lipid metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383512000950

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http://www.sciencedirect.com/science/article/pii/S2211383512000950

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