FAP and FAPI-PET/CT in Malignant and Non-Malignant Diseases: A Perfect Symbiosis?

FAP and FAPI-PET/CT in Malignant and Non-Malignant Diseases: A Perfect Symbiosis?

A fibroblast activation protein (FAP) is an atypical type II transmembrane serine protease with both endopeptidase and post-proline dipeptidyl peptidase activity. FAP is overexpressed in cancer-associated fibroblasts (CAFs), which are found in most epithelial tumors. CAFs have been implicated in pro...

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Bibliographic Details
Main Authors: Katharina Dendl, Stefan A. Koerber, Clemens Kratochwil, Jens Cardinale, Rebecca Finck, Mardjan Dabir, Emil Novruzov, Tadashi Watabe, Vasko Kramer, Peter L. Choyke, Uwe Haberkorn, Frederik L. Giesel
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
FAPI-PET/CT
FAP
CAFs
various malignancies
benign diseases
fibroblast
Online Access:https://www.mdpi.com/2072-6694/13/19/4946

Internet

https://www.mdpi.com/2072-6694/13/19/4946

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