Mucosal Administration of E-selectin Limits Disability in Models of Multiple Sclerosis

Mucosal Administration of E-selectin Limits Disability in Models of Multiple Sclerosis

E-selectin plays an important role in mediating the rolling of leukocytes along and thus, the subsequent extravasation across activated endothelial cells comprising the microvasculature of the blood brain barrier (BBB). In multiple sclerosis (MS) and other inflammatory disorders of the central nervo...

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Bibliographic Details
Main Authors: Jacqueline A. Quandt, Pierre Becquart, Emily Kamma, John Hallenbeck
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
multiple sclerosis
E-selectin
mucosal tolerance
experimental autoimmune encephalomyelitis
neuroinflammation
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00190/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2019.00190/full

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