In-Silico Studies toward the Improvement of the Antibacterial Activity of Pristinamycin IIB

Pristinamycin IIB (PIIB) is a potent antibiotic with limited use, due to some structural problems and also due to the bacterial resistance exhibited toward the antibiotic. A thorough study led to the design of novel analogues of PIIB, based on the introduction of a difluorostatone moiety. Herein, we...

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Bibliographic Details
Main Authors: Assia Chebieb, Chewki Ziani-Cherif, Khadidja Bellifa
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Chemistry Proceedings
Subjects:
Online Access:https://www.mdpi.com/2673-4583/8/1/13