Mechanically stimulated ATP release from murine bone cells is regulated by a balance of injury and repair

Bone cells sense and actively adapt to physical perturbations to prevent critical damage. ATP release is among the earliest cellular responses to mechanical stimulation. Mechanical stimulation of a single murine osteoblast led to the release of 70 ± 24 amole ATP, which stimulated calcium responses i...

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Bibliographic Details
Main Authors: Nicholas Mikolajewicz, Elizabeth A Zimmermann, Bettina M Willie, Svetlana V Komarova
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/37812