Hepatic Stellate Cells Improve Engraftment of Human Primary Hepatocytes: A Preclinical Transplantation Study in an Animal Model

Human hepatocytes are used for liver cell therapy, but the small number of engrafting cells limits the benefit of cell transplantation. We tested whether cotransplantation of hepatocytes with hepatic stellate cells (HSCs) could improve hepatocyte engraftment in vivo. Human primary hepatocytes were t...

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Bibliographic Details
Main Authors: Ange-Clarisse Dusabineza, Mustapha Najimi, Noémi Van Hul, Vanessa Legry, Dung Ngoc Khuu, Leo A. Van Grunsven, Etienne Sokal, Isabelle A. Leclercq M.D., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2015-12-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368915X686788